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L.2.01.408
Therapeutic phlebotomy commonly includes removal of whole blood from a patient to reduce red blood mass.
Therapeutic phlebotomy will be covered for following diagnoses only:
Polycythemia vera
Hemochromatosis
Primary erythrocytosis
Porphyria cutanea tarda
Secondary erythrocytosis
Congenital polycythemia
None
The coverage guidelines outlined in the Medical Policy Manual should not be used in lieu of the Member's specific benefit plan language.
10/1993: Approved by Medical Policy Advisory Committee (MPAC)
4/5/2001: Policy reviewed; Managed Care Requirements deleted
5/2/2002: Type of Service and Place of Service deleted
9/20/2002: Code Reference section updated
2/13/2004: Code Reference section reviewed, no changes
3/10/2006: Coding updated. CPT4/HCPCS 2006 revisions added to policy
12/31/2008: Policy reviewed, no changes
10/14/2010: Annual ICD-9 code update: 275.0 deleted/expanded to the fifth digit. Added 275.01 - 275.09 to the Covered Codes table.
03/10/2014: Policy reviewed; no changes.
08/14/2015: Medical policy revised to add ICD-10 codes.
06/06/2016: Policy number L.2.01.408 added.
07/25/2016: Code Reference section updated to make the following correction: ICD-10 diagnosis code E58.1 should be D58.1.
01/18/2023: Policy reviewed; no changes.
02/14/2024: Policy reviewed; no changes.
03/13/2025: Policy reviewed; no changes.
Laboratory Test Handbook
This may not be a comprehensive list of procedure codes applicable to this policy.
The code(s) listed below are ONLY medically necessary if the procedure is performed according to the "Policy" section of this document.
Code Number | Description | ||
CPT-4 | |||
86960 | Volume reduction of blood or blood product (eg, red blood cells or platelets), each unit | ||
99195 | Phlebotomy, therapeutic (separate procedure) | ||
HCPCS | |||
ICD-9 Procedure | ICD-10 Procedure | ||
ICD-9 Diagnosis | ICD-10 Diagnosis | ||
238.4 | Neoplasm of uncertain behavior of polycythemia vera | D45 | Polycythemia vera |
275.01 | Hereditary hemochromatosis | E83.110 | Hereditary hemochromatosis |
275.02 | Hemochromatosis due to repeated red blood cell transfusions | E83.111 | Hemochromatosis due to repeated red blood cell transfusions |
275.03 | Other hemochromatosis | E83.118, E83.119 | Other and unspecified hemochromatosis |
275.09 | Other disorders of iron metabolism | E83.10, E83.19 | Other and unspecified disorders of iron metabolism |
277.1 | Disorders of porphyrin metabolism | E80.0 - E80.29 | Disorders of porphyrin metabolism |
282.1 | Hereditary elliptocytosis | D58.1 | Hereditary elliptocytosis |
285.0 | Sideroblastic anemia | D64.0 - D64.3 | Sideroblastic anemia code range |
289.0 | Polycythemia, secondary | D75.1 | Polycythemia, secondary |
289.6 | Familial polycythemia | D75.0 | Familial polycythemia |
774.1 | Perinatal jaundice from other excessive hemolysis | P58.3 | Neonatal jaundice due to polycythemia |
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