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Medical Policy Search



Printer Friendly Version Thyroid Stimulating Hormone

Thyroid Stimulating Hormone

 

DESCRIPTION

Thyroid function studies are used to delineate the presence or absence of hormonal abnormalities of the thyroid and pituitary glands. These abnormalities may be either primary or secondary and often but not always accompany clinically defined signs and symptoms indicative of thyroid dysfunction. Laboratory evaluation of thyroid function has become more scientifically defined. Tests can be done with increased specificity, thereby reducing the number of tests needed to diagnose and follow treatment of most thyroid disease. Measurements of serum sensitive thyroid-stimulating hormone (TSH) levels, complemented by determination of thyroid hormone levels [free thyroxine (FT-4) or total thyroxine (T4) with Triiodothyronine (T3) uptake] are used for diagnosis and follow-up of patients with thyroid disorders.

Additional tests may be necessary to evaluate certain complex diagnostic problems or on hospitalized patients, where many circumstances can skew tests results. When a test for total thyroxine (total T4 or T4 radioimmunoassay) or T3 uptake is performed, calculation of the free thyroxine index (FTI) is useful to correct for abnormal results for either total T4 or T3 uptake due to protein binding effects.

 

POLICY

Thyroid function testing may be considered medically necessary to:
  • Distinguish between primary and secondary hypothyroidism
  • Confirm or rule out primary hypothyroidism
  • Monitor thyroid hormone levels (i.e. patients with goiter, thyroid nodules, or thyroid cancer)
  • Monitor drug therapy in patients with primary hypothyroidism
  • Confirm or rule out primary hyperthyroidism
  • Monitor therapy in patients with hyperthyroidism

Thyroid function testing may be medically necessary in patients with disease or neoplasm of the thyroid and other endocrine glands.

Thyroid function testing may also be medically necessary in patients with metabolic disorders; malnutrition; hyperlipidemia; certain types of anemia; psychosis and non-psychotic personality disorders; unexplained depression; ophthalmologic disorders; various cardiac arrhythmias; disorders of menstruation; skin conditions; myalgias; and a wide array of signs and symptoms, including alterations in consciousness; malaise; hypothermia; symptoms of the nervous and musculoskeletal system; skin and integumentary system; nutrition and metabolism; cardiovascular; and gastrointestinal system.

Thyroid testing may be considered medically necessary up to two times a calendar year in clinically stable patients.

More frequent thyroid testing may be considered medically necessary for patients whose thyroid therapy has been altered or in whom signs or symptoms of hyperthyroidism or hypothyroidism are present.

Follow-up thyroid testing may be considered medically necessary in patients with a personal history of malignant neoplasm of the endocrine system and patients on long term thyroid drug therapy.

 

POLICY EXCEPTIONS

 None

 

POLICY GUIDELINES

Services performed outside the clinical indications contained in this Medical Policy will be considered not medically necessary.

The coverage guidelines outlined in this Medical Policy should not be used in lieu of the Member's specific benefit plan language.

 

POLICY HISTORY

3/26/2009: Approved by Medical Policy Advisory Committee (MPAC) 

9/28/2009: Code reference section updated. New ICD-9 diagnosis codes 279.41, 279.49, 784.42, 784.43, 784.44, 784.51, 784.59 and 799.21, 799.22, 799.23 and 799.29 added to covered table. Added deleted statement to ICD-9 code 279.4, 784.5 and 799.2. Description revised for ICD-9 codes 784.49 and 793.99

12/01/2009: Policy Statement Section revised to define year as a calendar year for the statement, thyroid testing may be considered medically necessary up to two times a year in clinically stable patients.

01/15/2010:  Typographical error corrected, changed V57.00 to V67.00

11/18/2010:  Added the following ICD-9 codes to the Covered Codes table: 150.0 - 150.9, 151.0 - 151.9, 152.0 - 152.9, 153.0 - 153.9, 277.7, 530.0 - 530.9, 531.00 - 531.91, 532.00 - 532.91, 533.00 - 533.91, 534.00 - 534.91, 535.00 - 535.71, 555.0 - 555.9, 558.1 - 558.9, 560.0 - 560.9, 562.00 - 562.13, 564.00 - 564.9, 626.0 - 626.9, 780.2, 796.2, V10.03, V10.04, V10.05, and V10.43.

01/14/2011: Added ICD-9 codes 708.0 - 708.9 to the Covered Codes table.

01/24/2011: Added the following ICD-9 codes to the Covered Codes table: 627.0 - 627.9, 783.41, and 783.43.

02/23/2011: Added ICD-9 codes 346.00 - 346.93, 374.32, and 611.6 to the Covered Codes table.

05/09/2011: Added ICD-9 codes 259.0, 259.1, 314.00, and 314.01 to the Covered Codes table. 

06/16/2011: Added ICD-9 codes 234.8, 194.0 - 194.9, and 227.0 - 227.9 to the Covered Codes table. 

08/11/2011: Added ICD-9 codes 252.00 - 252.08 and 783.40 to the Covered Codes table. 

12/13/2011:  Added the following ICD-9 codes to the Covered Codes table:  268.9, 733.91, 611.1, 140.0 -165.9, 170.0 -176.9, 179 - 199.2, 200.00 - 208.98, 209.00 - 209.79, 230.0 - 234.9, and  V10.0 - V10.91.

05/08/2012:  Added 287.5, 374.55, and 567.82 to the Covered Codes table.

07/13/2012:  Added 070.54, 274.00 - 274.9, 333.94, and 701.2  to the Covered Codes table.

 

SOURCES

Medicare National Coverage Determinations Thyroid Testing Policy # 190.22

 

CODE REFERENCE

This is not intended to be a comprehensive list of codes. Some covered procedure codes have multiple descriptions.

The code(s) listed below are ONLY covered if the procedure is performed according to the "Policy" section of this document.

Covered Codes

Code Number

Description

CPT

84436Thyroxine; total
84439Thyroxine; free
84443Thyroid stimulating hormone (TSH)
84479Thyroid hormone (T3 or T4) uptake or thyroid hormone binding ratio (THBR)

ICD-9 Procedure

  

ICD-9 Diagnosis

017.50-017.56Tuberculosis of the thyroid gland
070.54 Chronic hepatitis C without mention of hepatic coma (Added 07-13-2012
140.0 -165.9,
170.0 -176.9,
179 - 199.2,
200.00 - 208.98,
209.00 - 209.79,
230.0 - 234.9, V10.0 - V10.91  
Cancer diagnoses code range (Added 12-13-2011)
150.0 - 150.9 Malignant neoplasm of esophagus (Added 11-18-2010)
151.0 - 151.9 Malignant neoplasm of stomach (Added 11-18-2010)
152.0 - 152.9Malignant neoplasm of small intestine, including duodenum  (Added 11-18-2010)
153.0 - 153.9Malignant neoplasm of colon (Added 11-18-2010)
183.0Malignant neoplasm of ovary
193Malignant neoplasm of thyroid
194.0-194.9Malignant neoplasm of other endocrine glands and related structures (Added 06-16-2011)
198.89Secondary malignant neoplasm of the thyroid
220Benign neoplasm of ovary
226Benign neoplasm of thyroid gland
227.0 - 227.9Benign neoplasm of other endocrine glands and related structures (Added 06-16-2011)
234.8Carcinoma in situ of other specified sites (Added 06-16-2011) 
237.4Neoplasm of uncertain behavior of other & unspecified endocrine glands
239.7Neoplasm of unspecified nature, thyroid gland
240.0-240.9Goiter specified and unspecified
241.0-241.9Nontoxic nodular goiter
242.00-242.91Thyrotoxocosis with or without goiter
243Congenital hypothyroidism
244.0-244.9Acquired hypothyroidism
245.0-245.9Thyroiditis
246.0-246.9Other disorders of thyroid
249.00-249.01Secondary diabetes mellitus without mention of complication
249.10-249.11Secondary diabetes mellitus with ketoacidosis
249.20-249.21Secondary diabetes mellitus with hyperosmolarity
249.30-249.31Secondary diabetes mellitus with other coma
249.40-249.41Secondary diabetes mellitus with renal manifestations
249.50-249.51Secondary diabetes with ophthalmic manifestations
249.60-249.61Secondary diabetes mellitus with neurological manifestations
249.70-249.71Secondary diabetes mellitus with peripheral circulatory disorders
249.80-249.81Secondary diabetes mellitus with other specified manifestations
249.90-249.91Secondary diabetes mellitus with unspecified complication
250.00-250.93Diabetes mellitus
252.00 - 252.08Hyperparathyroidism (Added 08-11-2011)
252.1Hypoparathyroidism
253.1Other and unspecified anterior pituitary hyperfunction
253.2Panhypopituitarism
253.3Pituitary dwarfism
253.4Other anterior pituitary disorders
253.7Iatrogenic pituitary disorders
255.2Adrenogenital disorders
255.41Glucocorticoid deficiency
255.42Mineralocorticoid deficiency
256.31-256.39Ovarian failure
257.2Testicular hypofunction
258.01Multiple endocrine neoplasia (MEN) Type I
258.02 Multiple endocrine neoplasia (MEN) Type II A
258.03 Multiple endocrine neoplasia (MEN) Type II B
258.9 Polyglandular dysfunction
259.0Delay in sexual development and puberty, not elsewhere classified (Added 05-09-2011)
259.1Precocious sexual development and puberty, not elsewhere classified (Added 05-09-2011)
262Malnutrition, severe
263.03-263.9Malnutrition, other and unspecified
266.0Ariboflavinosis
268.9Unspecified vitamin D deficiency (Added 12-13-2011)
272.0Pure hypercholesterolemia
272.2Mixed hyperlipidemia
272.4Other and unspecified hyperlipidemia
274.00 - 274.9Gout (Added 07-13-2012)
275.40-275.49Calcium disorders
275.5Hungry bone syndrome
276.0Hyposmolality and/or hypernatremia
276.1Hyposmolality and/or hyponatremia
277.7Dysmetabolic syndrome X (Added 11-17-10) 
278.3Hypercarotenemia
279.4Autoimmune disorder, not classified elsewhere (deleted 10-1-2009)
279.41Autoimmune lymphoproliferative syndrome (new 10-1-2009)
279.49Autoimmune disorder, not classified elsewhere (new 10-1-2009)
281.0Pernicious anemia
281.9Unspecified deficiency anemia
283.0Autoimmune hemolytic anemia
285.9Anemia, unspecified
287.5Thrombocytopenia, unspecified (Added 05-08-2012)
290.0Senile dementia, uncomplicated
290.10-290.13Presenile dementia
290.20-290.21Senile dementia with delusional or depressive features
290.3Senile dementia with delirium
293.0-293.1Delirium
293.81-293.89Other specified transient mental disorders due to conditions classified elsewhere
294.8Other persistent mental disorders due to conditions classified elsewhere
296.00-296.99Episodic mood disorders
297.0Paranoid state, simple
297.1Delusional disorder
297.9Unspecified paranoid state
298.3Acute paranoid reaction
300.00-300.09Anxiety states
307.9Other unspecified special symptoms or syndromes, not elsewhere classified
310.1

Personality change due to conditions classified elsewhere

311

Depressive disorder, not elsewhere classified

314.00Attention deficit disorder of childhood without mention of hyperactivity (Added 05-09-2011)
314.01Attention deficit disorder of childhood with hyperactivity  (Added 05-09-2011)
327.00Organic insomnia, unspecified
327.01Insomnia due to medical condition classified elsewhere
327.09Other organic insomnia
327.29Other organic sleep apnea
327.52Sleep related leg cramps
327.8Other organic sleep disorders
331.0, 331.11, 331.19, 331.2Alzeimer’s, pick disease, Senile degeneration of brain
331.83Mild cognitive impairment, so stated
333.1Essential and other specified forms of tremor
333.94 Restless legs syndrome [RLS] (Added 07-13-2012)
333.99Other extrapyramidal diseases and abnormal movement disorders
346.00 - 346.93Migraine (Added 02-23-2011)
354.0Carpel Tunnel syndrome
356.9Idiopathic peripheral neuropathy, unspecified polyneuropathy
358.1Myasthenic syndromes in diseases classified elsewhere
359.5Myopathy in endocrine diseases classified elsewhere
359.9Myopathy, unspecified
368.2Diplopia
372.71Conjunctival hyperemia
372.73Conjunctival edema
374.32Myogenic ptosis (Added 02-23-2011)
374.41Lid retraction or lag
374.55Hypotrichosis of eyelid (Added 05-08-2012)
374.82Eyelid edema
376.21Thyrotoxic exophthalmos
376.22Exophthalmic opthalmoplegia
376.30-376.31Exphthalmic conditions
376.33-376.34Orbital edema or congestion, intermittent exophthalmos
378.50-378.55Paralytic strabismus
401.0-401.9Essential hypertension
403.00-403.91Hypertensive heart and chronic kidney disease
423.9Unspecified disease of pericardium
425.7Nutritional and metabolic cardiomyopathy
427.0Paroxysmal supraventricular tachycardia
427.2Paroxysmal tachycardia, unspecified
427.31Atrial fibrillation
427.89Other specified cardiac dysrhythmia
427.9Cardiac dysrhythmia, unspecified
428.0Congestive heart failure, unspecified
428.1Left heart failure
429.3Cardiomegaly
511.9Unspecified pleural effusion
518.81Acute Respiratory failure
529.8Other specified conditions of the tongue
530.0 - 530.9Diseases of esophagus (Added 11-18-2010)
531.00 - 531.91Gastric ulcer (Added 11-18-2010)
532.00 - 532.91Duodenal ulcer (Added 11-18-2010)
533.00 - 533.91 Peptic ulcer, site unspecified  (Added 11-18-2010)
534.00 - 534.91Gastrojejunal ulcer (Added 11-18-2010)
535.00 - 535.71Gastritis and duodenitis (Added 11-18-2010)
555.0 - 555.9Regional enteritis of small intestine (Added 11-18-2010)
558.1 - 558.9Other and unspecified noninfectious gastroenteritis and colitis (Added 11-18-2010)
560.0 - 560.9Intestinal obstruction without mention of hernia (Added 11-18-2010)
562.00 - 562.13Diverticula of intestine (Added 11-18-2010)
564.00-564.9Functional digestive disorders, not elsewhere classified (Added 11-18-2010)
567.82Sclerosing mesenteritis (Added 05-08-2012)
568.82Peritoneal effusion (chronic)
611.1Hypertrophy of breast (Added 12-13-2011)
611.6Galactorrhea not associated with childbirth (Added 02-23-2011)
625.3Dysmenorrhea
626.0-626.9Disorders of menstruation and other abnormal bleeding from female genital tract (Added 11-18-2010)
627.0 - 627.9Menopausal and postmenopausal disorders (Added 01-24-2011)
648.10-648.14Other current conditions in mother, classifiable elsewhere, but complicating pregnancy, childbirth, or puerperium, thyroid dysfunction
676.20-676.24Engorgement of breast associated w/childbirth disorders of lactation
698.9Unspecified pruritic disorder
701.1Keratoderma, acquired (dry skin)
701.2  Acquired acanthosis nigricans (Added 07-13-2012)
703.8Other specified diseases of nail (Brittle nails)
704.00-704.09Alopecia
708.0-708.9  Urticaria (Added 01-14-2011)
709.1Vitiligo
710.0-710.9Diffuse disease of connective tissue
728.2Muscle wasting
728.87Muscle weakness (generalized)
728.9Unspecified disorder of muscle, ligament, and fascia
729.1Myalgia and myositis, unspecified<
729.82Musculoskeletal cramp
730.30-730.39Periostitis without osteomyelitis
733.02Idiopathic osteoporosis
733.09Osteoporosis, drug induced
733.91Arrest of bone development or growth (Added 12-31-2011)
750.15Macroglossia, congenital
759.2Anomaly of other endocrine glands
780.01Coma
780.02Transient alteration of awareness
780.09Alteration of consciousness, other
780.2Syncope and collapse (Add 11-17-10)
780.50Insomnia
780.51Insomnia with sleep apnea, unspecified
780.52Insomnia, unspecified
780.60Fever, unspecified
780.61Fever presenting with conditions classified elsewhere
780.62Postprocedural fever
780.63Postvaccination fever
780.64Chills (without fever)
780.65Hypothermia not associated with low environmental temperature
780.71Chronic fatigue syndrome
780.72Functional quadriplegia
780.79Other malaise and fatigue
780.8Generalized hyperhidrosis
780.93Memory loss
780.94Early satiety
780.96Generalized pain
780.97Altered mental status
780.99Other general symptoms
781.0Abnormal involuntary movements
781.3Lack of coordination, ataxia
782.0Disturbance of skin sensation
782.3Localized edema
782.8Changes in skin texture
782.9Other symptoms involving skin and integumentary tissues
783.0Anorexia
783.1Abnormal weight gain
783.21Abnormal loss of weight
783.40Lack of normal physiological development, unspecified  (Added 08-11-2011)
783.41Failure to thrive (Added 01-24-2011)
783.43Short stature (Added 01-24-2011)
783.6Polyphagia
784.1Throat pain
784.42Dysphonia (new 10-1-2009)
784.43Hypernasality (new 10-1-2009)
784.44Hyponasality (new 10-1-2009)
784.49Other voice and resonance disorders (description revised 10-1-2009)
784.5Other speech disturbance (deleted 10-1-2009)
784.51Dysarthria (new 10-1-2009)
784.59Other speech disturbance (new 10-1-2009)
785.0Tachycardia, unspecified
785.1Palpitations
785.9Other symptoms involving cardiovascular system
786.09Other symptoms involving respiratory system
786.1Stridor
787.20Dysphagia, unspecified
787.21Dysphagia, oral phase
787.22Dysphagia, oropharyngeal phase
787.23Dysphagia, pharyngeal phase
787.24Dysphagia, pharyngo-esophageal phase
787.29Other dysphagia
787.91-787.99Other symptoms involving digestive system
789.51Malignant Ascites
789.59Other Ascites
793.99Other nonspecific (abnormal) findings on radiological and other examination of body structure (description revised 10-1-2009)
794.5Thyroid, abnormal scan or uptake
796.1Other nonspecific abnormal findings, abnormal reflex
796.2Elevated blood pressure reading without diagnosis of hypertension (Added 11-18-2010)
799.2Nervousness (deleted 10-1-2009)
799.21Nervousness (new 10-1-2009)
799.22Irritability (new 10-1-2009)
799.23Impulsiveness (new10-1-2009)
799.29Other signs and symptoms involving emotional state (new 10-1-2009)
990Effects of radiation, unspecified
V10.03Personal history of malignant neoplasm of esophagus (Added 11-18-2010)
V10.04Personal history of malignant neoplasm of stomach (Added 11-18-2010)
V10.05Personal history of malignant neoplasm of large intestine (Added 11-18-2010)
V10.43 Personal history of malignant neoplasm of ovary (Added 11-18-2010)
V10.87Personal history of malignant neoplasm of thyroid
V10.88Personal history of malignant neoplasm of other endocrine gland
V12.2Personal history of endocrine, metabolic and immunity disorders
V58.69Long term (current) use of other medications
V67.00-V67.9Follow-up examination
HCPCS 
   None

 

 

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