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National Provider Identifier

Blue Cross & Blue Shield of Mississippi requires each provider have a unique National Provider Identifier (NPI) number when filing claims. The general guidelines for NPI claims submission include:

UB-04 Claims

  • Organizations should file the billing / organizational NPI number in field 56.
CMS-1500 Claims (Non-Hospital Based Professionals*)
  • Sole Practitioner without a billing NPI:
    • File the performing NPI number in field 24J and in field 33A.
  • Sole Practitioner with a billing NPI:
    • File the performing NPI number in field 24J and the billing NPI number in field 33A.
  • Clinic with multiple providers:
    • File the performing NPI number in field 24J and the billing NPI number in field 33A.

*Filing guidelines for hospital based professionals vary by hospital. If you submit claims for hospital-based professionals and need assistance with filing guidelines, please call our NPI Compliance Hotline at 1-877-643-5138.

How do I apply for an NPI?

If you need to apply for an NPI, you can use one of the three ways outlined below:

  1. Use the web-based National Plan and Provider Enumeration System (NPPES) online at https://nppes.cms.hhs.gov.
  2. Complete a paper application and mail it to the NPI Enumerator, the CMS contractor responsible for processing NPI applications. You may contact the NPI Enumerator by calling 1-800-465-3203 or 1-800-692-2326 (TTY). The mailing address is:

    NPI Enumerator
    P.O. Box 6059
    Fargo, ND 58108-6059

  3. Have your application information, with your permission, submitted to the NPPES electronically by an organization on your behalf.

For more information related to NPI, the following links provide provide quick and easy access to general information about the NPI:

  • NPI Overview
  • CMS Frequently Asked Questions about NPI
  • National Provider Identifier Glossary (PDF)
  • CMS Determination of Subparts (PDF)




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